4xx Client error responses
421Misdirected Request
Request directed at wrong server
#When does this occur?
Returned when the request was directed at a server that cannot produce a response. Can occur with HTTP/2 connection reuse.
#How to handle?
Send the request to the correct server. Create a new HTTP/2 connection or use the correct Host header.
#Example
HTTP Response
HTTP/1.1 421 Misdirected Request
Content-Type: application/json
Date: Tue, 10 Feb 2026 07:16:20 GMT
{
"status": 421,
"message": "Misdirected Request"
}#Related Status Codes
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